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John McDonnell, of Beloit, prepares to get a PET scan for a study on Alzheimer's disease at UW-Madison's Waisman Center. McDonnell, 73, does not have the disease. The study, involving a radioactive tracer called PIB, is one of many research efforts being expanded by the university's new designation as a national Alzheimer's Disease Research Center.

Bob Rowland, who has Alzheimer's disease, works a maze during memory tests at Madison's Veterans Hospital. He did well on tests of active thinking but had trouble remembering basic information from minutes before.

Barbara White (above), 49, of Madison, takes memory tests conducted by research specialist Sarah Sweney at UW-Madison's pharmacy building. White, whose mother and two aunts had Alzheimer's disease, is in the Wisconsin Registry for Alzheimer's Prevention, the country's largest study of middle-aged children of parents with the disease.

Bob Rowland, 76, of Mazomanie, performs memory tests conducted by research associate Kirsten Walth at Madison's Veterans Hospital. Rowland, a retired engineer, was diagnosed two years ago with Alzheimer's disease. A former handyman, he can no longer fix things, he said.

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